The Informatics Core of the Colorado Clinical & Translational Sciences Institute (CCTSI) provides secure, HIPAA-compliant infrastructure and expert services to support clinical and translational research across the University of Colorado Anschutz Campus and its affiliated institutions. The Core manages and maintains a suite of integrated systems - including servers, databases, and applications - that enable researchers to securely store, retrieve, and analyzes sensitive health data.
The CCTSI Informatics Core empowers translational researchers by providing the tools, infrastructure, and expertise needed to transform data into discovery. We help investigators:
The CCTSI Informatics Core provides secure, reliable, and scalable technology solutions to support research, clinical operations, and administrative workflow across the institution. Our services are designed to meet compliance requirements while enabling efficient data management and application development.
Capacity Note: New project intake is currently limited. We welcome discussions to help guide appropriate solutions.
Secure, HIPAA-compliant database hosting with managed backups, system maintenance, and scalable resources to support research and operational data needs.
Design, enhancement, and maintenance of web-based applications supporting grant, scientific, and protocol review workflows.
Compliant infrastructure with robust access control, system monitoring, and ongoing vulnerability management to ensure secure and reliable operations
Guidance on data governance, security, and best practices to support compliant and efficient data use.
Support for departmental websites and lightweight tools, including forms, calendars, and communication-focused solutions
Secure REDCap hosting and consultation for research and quality improvement projects.
REDCap is a free, auditable, HIPAA-compliant tool for the creation of study databases and surveys.
Project scope and pricing are defined through consultation and formal service agreements based on complexity and resource needs
Faculty and staff at the CU Anschutz Campus can explore and compare research computing resources through this tool, designed by the School of Medicine, Office of Regulatory Compliance, and Information Strategy and Services.
The Clinical Research Informatics & Innovation Unit (CRIIU) supports investigator-led research and digital health innovation at the CU Anschutz Campus and UCHealth. CRIIU specializes in integrating and customizing Epic and non-Epic clinical informatics systems to enable research embedded in clinical workflows. By providing technical expertise, data integration, and informatics infrastructure, CRIIU helps investigators develop scalable solutions that enhance research impact and improve competitiveness for external funding.
Compass integrates a variety of patient data from UCHealth, Children's Hospital of Colorado, CU Medicine (formerly UPI), and UC Denver. Health Data Compass restructures and harmonizes this data to make it more useful for a variety of uses. Data from UCHealth and CHCO goes back historically to 2011 and is current to the month.
Health Data Compass also integrates data on patients from UCHealth and Children's Hospital of Colorado electronic medical record (EMR) from other sources outside of the EMR such as the Colorado State Death Registry and CIVHC's All Payer Claims Database (APCD).
Children's Hospital Colorado |
UCHealth |
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| ACT |

Jayashree Kalpathy-Cramer, PhD
Director, Translational Informatics, CCSTI
Chief, Division of Artificial Medical Intelligence, Endowed Chair in Data Sciences, Dept. Ophthalmology
[email protected]

Thomas Yaeger, BS
Director of Research Informatics Consultation and Technology Services, CCTSI